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FOR ALPHA-GAL-AWARE DIGESTION

Mammal-free enzymes for every  kind of mealtime

Whether you’re seeking everyday digestive support or navigating pancreatic issues alongside alpha-gal, BoulderBio’s high potency enzymes are made for you. Meticulously crafted for Alpha-Gal Syndrome and 100% mammal-free.

Over 20,000 Happy Customers!

40,000 FIP Lipase

Full-spectrum activity

90 Vegan capsules

3

Targeted Enzymes

Lipase - Protease - Amylase

0

Mammalian Ingredients

Vegetable Cellulose Capsule

1

Transparent Formula

Patent Pending & Clean

Two Different Needs, One Shared Standard

Alpha-gal changes what "clean ingredients" means. Choose the path that sounds most like you.

1

EVERY DAY DIGESTIVE SUPPORT

You Already Use a Digestive Enzyme

Upgrade your routine with clearly listed, high-potency enzymes that support the breakdown of fats, proteins, and carbohydrates-without mammalian ingredients.

For Meals & Snacks

Broad-pH Enzyme Activity

Simply, Fully Disclosed Ingredients

2

ALPHA-GAL + PANCREATIC CONDITIONS

You need a more careful enzyme conversation

Navigating incomplete digestion is tough, but BoulderBio makes it easy. If you have alpha-gal syndrome and need clinically relevant pancreatic support, bring BoulderBio's mammal-free ingredient list to your clinician and discuss what fits your care plan.

No Porcine Pancrelipase

40,000 FIP Lipase per Capsule

Doctor Trusted Formula

1

EVERY DAY DIGESTIVE SUPPORT

You Already Use a Digestive Enzyme

Upgrade your routine with clearly listed, high-potency enzymes that support the breakdown of fats, proteins, and carbohydrates-without mammalian ingredients.

For Meals & Snacks

Broad-pH Enzyme Activity

Simply, Fully Disclosed

Ingredients

2

ALPHA-GAL + DIAGNOSED EPI

You need a more caretul enzyme conversation

Prescription PERT is typically made with porcine pancrelipase.

If you have EPI and alpha-gal syndrome, bring BoulderBio's mammal-free ingredient list to your clinician and discuss what fits your care plan.

No Porcine Pancrelipase

40,000 FIP Lipase per Capsule

A Formula Your Team Can

Review

BoulderBio is a dietary supplement and is not a replacement for prescribed pancreatic enzyme replacement therapy (PERT).

ALPHA-GAL AWARE BY DESIGN

Know What's In Every Capsule

Alpha-gal sensitivities are personal. BoulderBio keeps the ingredient list short, clear, and mammal-free so you and your healthcare provider can make a more informed choice.

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FULL-SPECTRUM SUPPORT

Three Enzymes. Clearly Dosed

Made through microbial fermentation and designed to support digestion across a broad pH range.

Clean Ingredients,

No plasticizers or phthalates

Clinically Dosed,

Rx Strength

Patent-pending formula works without an enteric coating

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Rated 4.8/5 from 133 Reviews

YOUR MAMMAL FREE ENZYME ROUTINE

Clear Ingredients. High Potency. No Compromise.

Therapeutic Strength Fermented Digestive Enzymes

90 Vegan Capsules

Made in the USA in a cGMP Facility

Patent-Pending Formula

Subscribe & Save 10%

30 day supply delivered monthly.

Pause or cancel anytime.

One-time purchase

$80.00

/every month

Clinically Grounded, Patient Trusted.

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Reclaim Your Gut Health

Combat Post-Meal Bloating

Enjoy Cleaner, Smoother Bowel Movements

Enhance Nutrient Absorption

Alleviate Gas & Stomach Cramps

Reduce Mealtime Stress

Frequently Asked Questions

Customer Reviews

Based on 139 reviews
91%
(126)
4%
(6)
1%
(2)
1%
(2)
2%
(3)
R
Robert E Sweat
A
Anonymous
Lifesaver

I was really struggling with pancreatic insufficiency until I got on Boulder Bio’s Digestive Enzymes! What a lifesaver & so much more affordable than the pharmaceuticals big name solutions!

A
Anonymous
Great product, excellent customer service

This product has been really helpful, and I had a great experience with their customer service when I needed help with my order!

D
Dyan Schecterson
This Changed My Life!

As a person diagnosed and living with Exocrine Pancreatic Insufficiency (EPI) for a while, this product was a game-changer! Since having my gallbladder removed 14 months ago, I have had chronic problems with digestion. My doctor, whom I appreciate because he is always seeking more homeopathic paths to health, informed me that the "standard treatment" is Pancreatic Enzyme Replacement Therapy (PERT). CREON is one in a handful of pharmaceutical medications used in PERT. PERT is porcine (pig) pancreatic enzymes. It is used because the porcine pancreatic enzyme is "similar" to the human. As a lacto-ovo vegetarian for 45 years, it was a challenge to consider consuming pork -- no matter the form. I began intensively researching EPI and it's treatment.

Global research, studies, and clinical trials were available. I learned about fungal enzyme treatments that have been used worldwide. Then I found Boulder Bio. Their website was informative and prompted more investigation. I hand-delivered pages of info I had compiled to my Dr, telling him that I wanted to try the BoulderBio Digestive Enzymes first, before jumping onto the PERT path.

Well, after living on watermelon and canned pears for a long time, I decided to try the Digestive Enzymes from Boulder Bio. WHAT A GAME-CHANGER!

I take 1 capsule before eating my regular foods and no longer experience the intense bloating, abdominal cramping, nausea, or diarrhea. After one week, I was completely sold on this product and have shared my experience with many who have digestive challenges.

Customer service at Boulder Bio is stellar! This is an American company intent on producing the best product....and they do. Try it!

M
Marilyn Drake
Help At Last

In September 2025 I thought I had gotten bad food at a restaurant as I had diarrhea. After two weeks I was still dealing with having to stay home. I had a close relationship with the bathroom. I finally got an appointment with my primary care and she ordered some stool tests. One came back as mild Exocrine Pancreatic Insufficiency which I had never heard about before. I would not call it mild.m Next came an appointment with a Gastrointerologist. She recommended a prescription for enzymes. My insurance wanted a $254 co-pay which I balked at. Went home and did research on the internet and soon found Boulder Bio. Certainly glad I did. I ordered a bottle to see if it would work. It took a week or two for my system to adjust to the enzymes and I became regulated. I only have to take one pill a day and can now leave the house to go to church, go shopping and travel without worrying whether I will have an accident. I am 84 yrs. Old and extremely glad I found Boulder Bio. Thank you.

A
Anonymous
Noticeable difference

I notice a big difference when I forget to take Boulderbio with each meal. It takes my body a minute to realize that help is on the way, but as soon as I take it for a full day, I am back to feeling good with energy.

M
Maureen Gochee
Changed my life

I have Alpha Gal Syndrome and pancreatic problems. These enzymes are mammal free.

A
Anonymous
Affordable alternative to Creon

After my Whipple procedure, I was prescribed Creon, which worked well, but even with insurance it was way too expensive. Looking for a more affordable option, I found Boulder Bio digestive enzymes and decided to give them a try.

It takes time to find the right dose, and I’m still not quite there yet, but they work well and have been comparable to Creon. While Boulder Bio’s cost is still on the higher end of over-the-counter digestive enzymes, the quality is better than other cheaper brands, and the cost is more manageable than Creon. I’m glad to have found an effective alternative that supports my digestion without the hefty prescription price tag.

J
Judith Fazzolari
Miracle medicine!

I was in so much pain before I tried Boulder Bio. Sadly I discovered that I am allergic to the pig pancreas enzyme. Severe reaction. I’ve been pain free since taking it - 3 capsules with each meal and 2 with a snack. Wonderful!

J
Jeffy Griffin
Whipple support

Unfortunately, your enzymes are not working as well as CREON. I’m getting more bile reflux and am not feeling good when I eat. I’m not tolerating as many foods as I was before I switched to your enzymes. I was looking for a more affordable pancreatic enzyme as CREON has gone through the roof.